ea0065oc1.6 | Metabolism and Obesity | SFEBES2019
Akalestou Elina
, Noriega Livia Lopez
, Chabosseau Pauline
, Leclerc Isabelle
, Rutter Guy
Background: Both metabolic surgery and sodium glucose co-transporter (SGLT2) inhibitors have been demonstrated to improve insulin sensitivity and glucose clearance, but also increase glucagon secretion and cardiovascular health.Aim: To examine the effect of metabolic surgery (Vertical Sleeve Gastrectomy; VSG) on SGLT2 expression in kidney cortex of lean mice.Methods: In order to assess whether exogenous SGLT2 inhibition has the sam...